Dr. Leamon is the former Chief Scientific Officer at Fusion Pharmaceuticals where he led the Discovery efforts for novel actinium-225 based cancer targeted therapeutics, including 225Ac-FPI-2265 (ALPHA-BREAK phase 2/3 trial)
and helped facilitate the Company’s 2024 $2.4B acquisition by Astra Zeneca. Prior to Fusion Dr. Leamon was a scientific co-founder and Vice President of R&D at Endocyte, Inc. spanning 23 years of organization building to develop tissue-targeted agents for cancer, inflammation and polycystic kidney disease. These efforts included radiopharmaceutical imaging (SPECT and PET), radioligand therapy (RLT; targeted alpha and beta therapy), targeted chemotherapeutics (SMDC; ADC), immune (CAR-T) and gene therapy projects. Development programs at Endocyte included etarfolatide (99mTc-EC20; phase 3 for companion imaging), vintafolide (a folate-vinca therapeutic; PROCEED phase 3 trial) and Pluvicto (177Lu-PSMA-617; VISION phase 3 trial) until the Company’s 2018 $2.1B acquisition by Novartis. Prior to Endocyte he was a leader in targeted drug delivery research at both GlaxoSmithKline, Inc. and Ionis Pharmaceuticals, Inc.
Dr. Leamon received an ACS-certified B.S. degree in Chemistry from Baldwin Wallace University (1988) and a Ph.D. in Chemistry from Purdue University (1993). He has spent over 36 years working in the drug delivery field and is also credited for conducting groundbreaking experiments in folate-targeted technology as well as for exemplifying this novel therapeutic approach for treating cancer. Dr. Leamon has published over 90 articles and is an inventor on 70 issued or submitted patents involving drug targeting. In 2015 he also received the American Chemical Society, George and Christine Sosnovsky Award for Cancer Research.
Dr. Leamon is currently serving on the board of directors of three privately held biotechnology companies, including EndPath Radiotherapeutics (also joining as CSO in June 2026), Ironfist Therapeutics and Inversion Therapeutics.